Treatment of severe pulmonary hypertension secondary to scleroderma: a three-drug approach.
نویسندگان
چکیده
We present a case of scleroderma complicated by severe pulmonary hypertension. The use of a three-drug (bosentan, iloprost, and sildenafil) approach contributed to significant improvement of both the clinical conditions and the pulmonary hemodynamics. Combining three pulmonary vasodilators with different mechanisms of action could benefit patients with severe pulmonary hypertension resistant to conventional therapy.
منابع مشابه
Drug treatment of scleroderma.
Scleroderma or systemic sclerosis is a rare condition with many clinical manifestations including Raynaud's phenomenon. As with many other rarely encountered diseases, drug therapy for scleroderma is often empirical with little evidence in the form of randomised controlled trials to aid drug choice. Raynaud's phenomenon has been recognised for well over 100 years. A considerable number of clini...
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ورودعنوان ژورنال:
- Internal medicine
دوره 47 6 شماره
صفحات -
تاریخ انتشار 2008